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Any test. Anywhere. Everyone.™

Baebies Technology

Baebies’ Platforms are powered by Digital Microfluidics, enabling Molecular, Chemistry, Coagulation and Immunoassays near-patient in minutes, using just a drop of sample

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What is Digital Microfluidics?

Digital microfluidics is a paradigm in which complex bioassay protocols are executed using a simple toolkit of droplet operations such as dispensing, transporting, mixing, and disposal. Droplets are manipulated through electrical control of surface tension (electrowetting). Tiny droplets are transported omnidirectionally on a printed circuit board substrate with utmost versatility allowing complex droplet operations.

Because of the discrete nature of the liquid volumes – as well as the synchronization and programmability of the fluid manipulations – this technique has been referred to as “digital microfluidics.” Many of the original inventors of digital microfluidics are on the Baebies team. Baebies’ technology is protected by over a couple hundred patents.

Here’s how it works

  1. An array of surface electrodes is layered by another plate to form a chamber in which the droplets are sandwiched.
  2. The remaining space is filled with an immiscible filler fluid to prevent evaporation of the droplets and to facilitate droplet transport.
  3. In this system, droplets can be transferred between any two neighboring electrodes and can be transported anywhere within a network of adjoining electrodes.
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Digital Microfluidics enables

Any Test: Any complex assay protocol is built up with a simple toolkit of droplet operations.

Anywhere: Liquid pumping is all-electronic, resulting in a small instrument.

Everyone: Droplet operations are compatible with any liquid sample (e.g., blood, plasma, urine, swab).

Chemistry

Whole blood separated into plasma for rate kinetic fluorimetric enzymatic assays

Molecular

Multiplex molecular assay in minutes with all sample prep, processing, and RT-PCR within the cartridge

Immunoassay

Heterogenous sandwich immunoassay with fluorimetric readout

Coagulation

Whole blood separated into plasma for coagulation assays

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Manufacturing

At Baebies we know that a person’s life or quality of life depends on our products, therefore we are dedicated to developing, delivering, and supporting high quality and cost effective products, and to continuously improving our technology, our team, our tools, and our processes through innovation.

Baebies has implemented and maintains a Quality Management System that fulfills the requirements of ISO 13485:2016. Cartridges are manufactured under strict quality control because we see the patient on the other side of each test that is manufactured here. At Baebies, every test matters because behind every test is a patient—and every test is an opportunity to save a life.

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Awards

Baebies’ Digital Microfluidic Technology Won the Coveted ADLM (Association for Diagnostics & Laboratory Medicine, formerly AACC) Disruptive Technology Award, the People’s Choice Award, and several other prestigious accolades.

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Related Links

PCR Testing in Minutes with Digital Microfluidics

Digital microfluidics (DMF) technology miniaturizes RT-PCR protocols using standard laboratory chemistries – but fully automated. Low reaction volumes enable rapid thermal cycling due to low thermal mass which helps speed up PCR.

5 Things to Know about Testing with Digital Microfluidics

Digital microfluidics is a method to programmably manipulate tiny droplets of liquid by electrical control of surface tension (or electrowetting).

Near-Patient Digital Microfluidics G6PD Assay

A near-patient digital microfluidics (DMF) glucose-6-phosphate dehydrogenase (G6PD) assay was used to estimate the prevalence of G6PD deficiency in a pediatric African American cohort.