To demonstrate that different assays can be performed on the same digital microfluidic cartridge, this study demonstrated feasibility of performing an enzyme assay for biotinidase deficiency on the same cartridge used for detecting enzyme activity of lysosomal storage disorders.
Authors: Carrie Graham, Ramakrishna S. Sista, Jairus Kleinert, Ning Wu, Allen Eckhardt, Deeksha Bali, David S. Millington, and Vamsee K. Pamula
Clin Biochem. 2013 December; 46(18): 1889–1891. doi:10.1016/j.clinbiochem.2013.09.003.