Near-Patient Digital Microfluidics G6PD Assay

Preliminary Investigation into the Prevalence of G6PD Deficiency in a Pediatric African American Population using a Near-Patient Diagnostic Platform

In this study, a near-patient digital microfluidics (DMF) glucose-6-phosphate dehydrogenase (G6PD) assay was used to estimate the prevalence of G6PD deficiency in a pediatric African American cohort.

Glucose-6-phosphate dehydrogenase deficiency (G6PDD) is an X-linked disorder and the most common enzyme deficiency in humans, with a high prevalence in persons of African, Asian, and Mediterranean descent. Neonates with undetected G6PDD are at risk for extreme hyperbilirubinemia.