Resources

Publications

Lysosomal storage disorder screening implementation: findings from the first six months of full population pilot testing in Missouri
Patrick V. Hopkins, Carlene Campbell, Tracy Klug, Sharmini Rogers, Julie Raburn-Miller, Jami Kiesling
J Pediatr. 2015 Jan;166(1):172-7. doi: 10.1016/j.jpeds.2014.09.023. Epub 2014 Oct 18. (not freely available)

Point-of-Care Quantitative Measure of Glucose-6-Phosphate Dehydrogenase Enzyme Deficiency
Vinod K. Bhutani, Michael Kaplan, Bertil Glader, Michael Cotten, Jairus Kleinert, Vamsee Pamula
Pediatrics. 2015 Nov;136(5):e1268-75. doi: 10.1542/peds.2015-2122. Epub 2015 Oct 12. (not freely available)

Novel application of digital microfluidics for the detection of biotinidase deficiency in newborns
Carrie Graham, Ramakrishna S Sista, Jairus Kleinert, Ning Wu, Allen Eckhardt, Deeksha Bali, David S Millington, and Vamsee K. Pamula
Clin Biochem. 2013 December ; 46(18): 1889–1891. doi:10.1016/j.clinbiochem.2013.09.003.

Multiplex Newborn Screening for Pompe, Fabry, Hunter, Gaucher, and Hurler Diseases Using a Digital Microfluidic Platform
Ramakrishna S. Sista, Tong Wang, Ning Wu, Carrie Graham, Allen Eckhardt, Theodore Winger, Vijay Srinivasan, Deeksha Bali, David S. Millington, and Vamsee K. Pamula
Clin Chim Acta. 2013 September 23; 424: 12–18. doi:10.1016/j.cca.2013.05.001.

Rapid assays for Gaucher and Hurler diseases in dried blood spots using digital microfluidics
Ramakrishna S. Sista, Tong Wanga, Ning Wu, Carrie Graham, Allen Eckhardt, Deeksha Bali, David S. Millington, and Vamsee K. Pamula
Mol Genet Metab. 2013 June ; 109(2): 218–220. doi:10.1016/j.ymgme.2013.03.010.

Novel microfluidic platform for automated lab-on-chip testing of hypercoagulability panel.
Emani S, Ramakrishna Sista, Loyola H. Trenor III C, Vamsee Pamula, Emani S.
Blood Coag and Fibrinolysis 2012, 23: 760-768. (not freely available)

Digital Microfluidic Platform for Multiplexing Enzyme Assays: Implications for Lysosomal Storage Disease Screening in Newborns
Ramakrishna S. Sista, Allen E. Eckhardt, Tong Wang, Carrie Graham, Jeremy L. Rouse, Scott M. Norton, Vijay Srinivasan, Michael G. Pollack, Adviye A. Tolun, Deeksha Bali, David S. Millington, and Vamsee K. Pamula
Clinical Chemistry 57:10 1444–1451 (2011)

Digital Microfluidics: A Future Technology in the Newborn Screening Laboratory?
David S. Millington, PhD, Ramakrishna Sista, PhD, Allen Eckhardt, PhD, Jeremy Rouse, Deeksha Bali, PhD, Ronald Goldberg, MD, Michael Cotten, MD, Rebecca Buckley, MD, and Vamsee Pamula, PhD
Semin Perinatol. 2010 April ; 34(2): 163–169. doi:10.1053/j.semperi.2009.12.008.

Conference Presentations

Krabbe and Niemann-Pick disorders: Development of novel fluorimetric assays using dried blood spots
D. Bali, H. Pham, C. Graham, P. Ross, M. Nuffer, S. Norton, R. Singh, A. Ullal, V. Pamula
Presented at 2016 LSD World Symposium (Feb 29-Mar 4, 2016 in San Diego, CA)

Point-of-Care Newborn Screening Using Whole Blood for Hyperbilirubinemia and G6PD Deficiency: Results from a Clinical Evaluation Using Digital Microfluidics
J. Kleinert, M. Castillo Cuadrado, C. Cotten, R. Goldberg, L. Katakam, V. Bhutani, and V. Pamula
Presented at 2014 Pediatric Academy Society Annual Meeting (May 3-6, 2014 in Vancouver, British Columbia, Canada)

Towards point-of-care nucleic acid testing for congenital cytomegalovirus infection in newborns
Lisa Nelson, Sunil Pati, Suresh Boppana, MD, and Vamsee Pamula, PhD
Presented at 2015 Congenital CMV Conference (April 20-24, 2015 in Brisbane, Australia)